Unravelling the Antioxidant Potential of Resveratrol and Quercetin in Animal Models: A Comprehensive Review

Ioana Craciun; Florinel Gheorghe Brudasca

doi:10.52331/cvj.v28i1.44

Authors

Ioana Craciun USAMV Cluj Napoca
Florinel Gheorghe Brudasca Department of Infectious Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea Mănăştur nr. 3-5, 400372 Cluj-Napoca, Romania

DOI:

https://doi.org/10.52331/cvj.v28i1.44

Keywords:

polyphenols, therapeutic implications, animal models

Abstract

Resveratrol and quercetin are naturally occurring polyphenolic compounds widely studied for their potential health benefits, particularly their antioxidant properties. This abstract provides an overview of the extensive research conducted on resveratrol and quercetin as antioxidants in animal models, highlighting their mechanisms of action and therapeutic potential. Animal models, such as rodents, have been instrumental in elucidating the oxidative stress pathway and evaluating the efficacy of various antioxidants. Resveratrol and quercetin have demonstrated significant antioxidant effects in animal models through multiple mechanisms. These include direct scavenging of reactive oxygen species (ROS), upregulation of endogenous antioxidant enzymes, inhibition of lipid peroxidation, and modulation of oxidative stress-related signaling pathways.

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