STRONGYLS BENZIMIDAZOLE RESISTANCE IN EQUINE FROM ZOO

Abstract

The research in view of establishing the development and the way in which antihelmintical treatment influences epidemiological indexes, was carried out between October 2008 and May 2009 in equine species from zoos.

In the zoo located Targu Mures it was noticed am strongyls intensity of 2300 EPG - 8700 LPG in horses, and 700 EPG - 1400 LPG in ponies. In vitro effectiveness of bemzimidazoles (BZ) being low in both horses and ponies. In the zoo located in Turda the intensity of the strongyl parasitism reached the level of 900 EPG - 2300 LPG in horses and 2400EPG - 2800 LPG in ponies, the effectiveness of the benzimidazoles being low. In the zoo located in Baia Mare the intensity of strongyls infestation was of 900 EPG - 1600 LPG in horses, 1900 EPG – 2600 LPG in ponies, 900 EPG -1500 LPG in donkeys benzimidazoles treatment being proven effective.

Cyathostomum species are considered as having the most significant pathology in equines. Worldwide, anthelmintical treatment, especially in strongylatosis, faces an ever-increasing phenomenon of drug resistance, to phenotiazin, thiabendazole as well as other BZ and ProBZ, in the strongyls population. The lack of success in treatment using drug combinations (piperazin and phenotiazin; triclorfon and phenotiazin; diclorfos and morantel) have spurred the development of new substances to which strongyls have not developed resistance. Tong time treatment with the same substance leads to the development of drug-resistant strongyl population, thus a low effectiveness, below the desired level.