The relationship between Stage B1 Myxomatous Mitral Valve Disease and Cardiac Weight in Dogs: a study on 19 patients
DOI:
https://doi.org/10.52331/1d1jh711Keywords:
dog, MMVD stage 1, heart weightAbstract
Myxomatous mitral valve disease (MMVD) is a prevalent heart condition in dogs, particularly affecting the mitral valve. Stage B1 of MMVD, as per the American College of Veterinary Internal Medicine (ACVIM) guidelines, encompasses asymptomatic dogs with structural heart disease. This stage is characterized by a range of radiographic and echocardiographic findings without significant cardiac remodeling. Despite its prevalence, the impact of MMVD Stage B1 on cardiac weight remains unclear. In this study, 28 dogs were examined to evaluate if MMVD Stage B1 correlates with abnormal increases in heart weight postmortem. Dogs were clinically examined, underwent echocardiography, and were divided into two groups based on MMVD staging. Heart weight relative to body weight (hW/bW) was assessed. Results revealed that MMVD Stage B1 had minimal impact on heart weight, with hW/bW ratios remaining within normal ranges. Notably, despite differences in breed, sex, and age, hW/bW ratios did not significantly deviate from normal values. This study provides valuable insights into the relationship between MMVD Stage B1 and cardiac weight in dogs, indicating the need for further investigations with larger sample sizes to validate these findings. Understanding cardiac weight alterations in MMVD can aid in refining diagnostic and management approaches for affected dogs.
References
Keene, B. W., Atkins, C. E., Bonagura, J. D., Fox, P. R., Häggström, J., Fuentes, V. L., ... & Uechi, M. (2019). ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of veterinary internal medi-cine, 33(3), 1127-1140.
Petrič, A. D. (2015). Myxomatous mitral valve disease in dogs-An update and perspectives. Macedonian veterinary review, 38(1), 13-20.
Fox, P. R. (2012). Pathology of myxomatous mitral valve disease in the dog. Journal of Veterinary Cardiology, 14(1), 103-126.
Parker, H. G., & Kilroy-Glynn, P. (2012). Myxomatous mitral valve disease in dogs: does size matter?. Journal of veterinary cardiology, 14(1), 19-29.
Queiroz, L. L., Moura, L. R., & Moura, V. M. B. D. (2018). Morphometric assessment of canine heart without macroscopically visible changes caused by cardiac disease. Ciência Animal Brasileira, 19, e43748.
Bienvenu, J. G., & Drolet, R. (1991). A quantitative study of cardiac ventricular mass in dogs. Canadian Journal of Veterinary Research, 55(4), 305.
Robinson, W.F., Robinson, N.A.: Cardiovascular System. In Jubb, Kennedy & Palmer’s Pathology of Domestic Animals - volume 3. 6th edition. Edited by Maxie MG. London: Elsevier Saunders. 2015;1–101.
Carvalho, L. M. M., Andrade, F. H. E., Alves, F. R., Guerra, P. C., & Sousa, A. L. (2002). Morfometria cardíaca externa em cães adultos. Pesquisa em Foco, 10, 1-2.
Ghoshal, N.G.: Coração e artérias do carnívoro. In Anatomia dos Animais Domésticos. 5th edition. Edited by Getty R, Sisson S, Grossman JD. Rio de Janeiro: Guanabara Koogan. 1986;1497–1549
Wyatt, H. L., Haendchen, R. V., Meerbaum, S., & Corday, E. (1983). Assessment of quantitative methods for 2-dimensional echocardiography. The American Journal of Cardiology, 52(3), 396-401.
Madsen, M. B., Olsen, L. H., Häggström, J., Höglund, K., Ljungvall, I., Falk, T., ... & Fredholm, M. (2011). Identification of 2 loci associated with development of myxomatous mitral valve disease in Cavalier King Charles Spaniels. Journal of Heredi-ty, 102(Suppl_1), S62-S67.
Olsen, L. H., Fredholm, M., & Pedersen, H. D. (1999). Epidemiology and inheritance of mitral valve prolapse in Dachs-hunds. Journal of veterinary internal medicine, 13(5), 448-456.
Pedersen, H.D. (2000). Mitral valve prolapse in the dog. Pathogenesis, pathophysiology and comparative aspects or early myxomatous mitral valve disease. PhD thesis, Copenhagen
Kittleson, M.D. (2005). Myxomatous mitral valve disease. In: Kittleson, M.D. and Kienle R.D. Small Animal Cardiovascular Medicine, Mosby
Chun, J. L., Bang, H. T., Ji, S. Y., Jeong, J. Y., Kim, M., Kim, B., ... & Kim, K. H. (2019). A simple method to evaluate body condi-tion score to maintain the optimal body weight in dogs. Journal of animal science and technology, 61(6), 366.
Laflamme, D. R. P. C., Developmental and validation of a body condition score system for dogs. (1997): 10-15.
Schoning, P., Erickson, H., & Milliken, G. A. (1995). Body weight, heart weight, and heart-to-body weight ratio in grey-hounds. American journal of veterinary research, 56(4), 420-422.
Werner, P. R., Bolson, J., & Battisti, M. K. B. (2001). Morfometria cardíaca para o diagnóstico de cardiopatias em cäes. Arq. ciênc. vet. zool. UNIPAR, 181-188.
Downloads
Published
Issue
Section
Categories
License
Copyright (c) 2024 Maria Cerbu, Ionel Papuc

This work is licensed under a Creative Commons Attribution 4.0 International License.